Meta-analysis of AUDIT scores in the UK biobank and 23andme participants of European ancestry (rs1229984 was not available in 23andme (Sanchez-Roige et al., 2017)) showed rs138495951, in ADH1B, was strongly associated with total AUDIT score (p = 10.7×10−36) (Sanchez-Roige et al., 2018); that SNP (and other associated SNPs in the region) is in LD with rs1229984 (D’ = 1; r2 = 0.54) (Supplementary Figure 2)
