Chunk #24 — Materials and Methods — Effects of intra-amygdala infusions — Amygdala infusion of AM3506

Source

Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity.

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Text

AM3506 (0 or 0.1 μg/μl) was bilaterally infused into the BLA 30 min before extinction training. The purpose of this experiment was to test whether the application of AM3506 to the amygdala was sufficient to produce an extinction-facilitating effect. The effect of drug treatment on freezing during retrieval was statistically analyzed using Student's t-test.