Chunk #18 — Materials and Methods — Effects of systemic AM3506 treatment — Pre-context-only treatment

Source

Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity.

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yes

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Here, the extinction session was replaced with an equivalent length session in which there were no CS presentations in context B. AM3506 was administered at a dose of 0 or 1.0 mg/kg 60 min before context exposure. The purpose was to test whether AM3506 reduced long-term fear in the absence of extinction training.