Figure 2c shows the results for five physical health phenotypes that are known or believed to be risk factors for various adverse health outcomes: body mass index (BMI), ever-smoker status, coronary artery disease, fasting glucose, and triglycerides. The estimated genetic correlations are all small in magnitude, consistent with earlier work, although the greater precision of our estimates allows us to reject null effects in most cases. The signs are generally consistent with those of the phenotypic correlations reported in earlier work between our phenotypes and outcomes such as obesity22, smoking23,24, and cardiovascular health25.
