The CeA and PL DV genes also were enriched in single network modules, blue and brown, respectively. Annotation of these modules was similar to that for the SH magenta module, e.g., a significant enrichment in genes associated with cell to cell signaling. The SH magenta, the CeA blue and the PL brown modules were significantly different in size (231, 773, and 593 genes, respectively). However, 183 (79%) the genes in the SH module are also found in the CeA and PL modules. This grouping of module core genes is found in Supplementary Table S9. This core grouping contains several receptors including Adra1a, Chrna7, Grin2b, Htr2a, Oprd1, and Sstr4; this core group also contains 17 protocadherins including 14 of the 22 known γ protocadherins. Thirty significant DV genes were identified as common to all three regions (see Figure 2); 25 genes of this group are found in the core module grouping. Within the core module grouping, we identified the 18 genes that were hub nodes across all three regions; we next aligned these genes with the 25 common DV genes found
