We identified 403 genes that are either within or overlap the 108 loci identified by the PGC. Once more at a liberal threshold of 1.2 × 10−4, correcting only for the number of genes and ignoring multiple endophenotypes, the VT identified no significant association between any gene and any of the endophenotypes. SKAT with a MAF threshold of 0.01 also failed to identify associations, although changing the MAF threshold to 0.05, we report one gene (strawberry notch homolog 1; SBNO1) on chromosome 12 that was significantly associated with pleasant difference startle (p = 4.19 × 10−5), although this did not survive correction for multiple testing of 403 genes.
