The results of the association tests for personality and psychological distress measures in the LBC1936 are shown in the Online Resource Table 1, these will be described. No SNPs surpassed the Bonferroni corrected significance level for any of the traits. However, for agreeableness, there were a larger number of nominally significant findings (p < .05) than for the other measures: 10 for the IPIP and six for the NEO. For IPIP agreeableness all of the nominally significant SNPs were located in the SYNJ2 gene (in independent SNPs), more than would be expected by chance (with .05 probability) assuming 44 tests. For NEO agreeableness, an additional SNP (rs2254562) was observed in the SYNJ1 gene. The most significant SNP for agreeableness, located in SYNJ2, was rs12202135 (p = .0003 for IPIP; p = .01 for NEO); MAF of this SNP was 0.13. Ten SNPs were nominally significant for depression, with all of these located in SYNJ2 (more than expected by chance); the most significant SNP was rs10046389 (p = .004) with a MAF of 0.40. Another of these SNPs (rs1750043) was also
