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Chunk #28 — Results

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Alcohol use disorder is associated with altered frontomedial phase-amplitude coupling strength during resting state.
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in text are prefixed with abbreviated indicator of sex either ‘W’ or ‘M’.⁃ Corrected p-value (PFDR) derived using Benjamini-Hochberg correction for multiple comparisons using raw p-values within specified cluster domain from S, the matrix of significance values derived from analysis of PAC comodulograms grouped by AUD diagnosis. Only candidate clusters with PFDR ≤ 0.05 were included in the next step of cluster validation.⁃ U (cluster) and p-value (cluster) are derived from groupwise comparisons of PAC strength for the candidate cluster, where PAC strength for each participant was represented by the median of all PAC values falling within the boundaries of the cluster PA domain, (FP1 - FP2), (FA1 - FA2), analyzed using Mann-Whitney U test.⁃ Common language effect size (CLES) indicates the probability of PAC being greater for someone randomly selected from the AUD group compared to someone randomly selected from the unaffected group.⁃ The rank biserial correlation coefficient, r, with range [-1,1], represents the magnitude and direction of the relationship between AUD diagnosis and ordinal dependent variable of ranked PAC strength.⁃ Significant PAC clusters in bold text and yellow highlighting. p ≤ 0.05 ∗, p ≤ 0.01 ∗∗.