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Chunk #18 — Metabolism, Metabolic Disease and CTRP3 — Human studies

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C1q/TNF-Related Protein 3 (CTRP3) Function and Regulation.
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Only one study has examined the effects of exercise on circulating CTRP3 levels in human subjects. Briefly, Choi et al. (2013) examine changes to circulating CTRP3 levels after a 3-month exercise program (45 min cardio/20 min resistance 5×/week) in 76 obese Korean females (10). They found that CTRP3 levels decreased ~15% (444-374 ng/mL) after exercise intervention. The exercise training program also resulted in ~9% loss in body weight, so it is unclear if the change in CTRP3 levels are due to exercise or the reduction in body fat. The effects of acute exercise or exercise training on CTRP3 levels in a healthy human population or in the absence of weight loss have not been investigated.