Five noteworthy patterns emerge from the comparison of these extreme conditions. First, estimates from model A1 (~PRS) are inflated relative to the true effect size. Inflation of the model A1 effect size increases when the correlation between PRS and environment (rGE) is higher. The A1 PRS effect is inflated approximately 150% in the rGE=0.1 conditions and approximately 350% in the rGE=0.5 conditions.
