input gene list based on Transcriptome (gene expression), Proteome (protein domains and interactions), Regulome (TFBS and miRNA), Ontologies (GO, Pathway), Phenotype (human disease and mouse phenotype), Pharmacome (Drug–Gene associations) and Bibliome (literature co-citation).Supported identifiers include NCBI Entrez gene IDs, approved human gene symbols, NCBI Reference Sequence accession numbers; single gene list.HTML output; Tab-delimited downloadable text file; graphical chartsToppGenePrioritize or rank candidate genes based on functional similarity to training gene list.Same as above but with two gene lists (training and test)HTML outputToppNetPrioritize or rank candidate genes based on topological features in protein–protein interaction network.Same as aboveHTML output; Cytoscape-compatible input file; graphical networksToppGeNetIdentify and prioritize the neighboring genes of the ‘seeds’ in protein–protein interaction network based on functional similarity to the ‘seed’ list (ToppGene) or topological features in protein–protein interaction network (ToppNet).Single gene listSame as above
