ToppFun can be used for gene list functional enrichment analysis. It uses as many as 14 annotation categories including GO terms, pathways, protein–protein interactions, protein functional domains, transcription factor-binding sites, microRNAs, gene tissue expressions and literatures. Flexible options are provided to either download results as a tab-delimited file or display as a chart. Hypergeometric distribution with Bonferroni correction is used as the standard method for determining statistical significance.
