Gene Set Enrichment Analysis database22 was used to obtain the list of spliceosomal proteins. Functional status of altered lncRNAs of interest was studied using “LncRNA Ontology” database23 which employs the pipeline based on transcriptional and epigenetic profiles of lncRNAs and protein-coding genes; default criteria set by developers were used to execute the ontology. Specifically, we mined for biological processes associated with specific lncRNA (individually), using the lncRNA-term associations at the confidence score of 100%. The resultant preliminary list included the query lncRNA, the inferred terms, the histone modification or expression used to infer the association, and other method(s) validating this association.
