Approximately 17 200 tests were performed as part of the autosomal gene-based analysis. Genomic control parameters indicated minimal inflation of the test statistics over the null value of 1.0; HA: 1.00, NS: 1.04, RD: 0.991, P: 0.963. The percentage of associations to be significant at the 0.05 level range from 4.7% with scale P to 5.5% with scales HA and RD. None of the scales resulted in gene-based associations that survived correction for multiple testing (17 261 tests and four scales, α=7.2 × 10−7). The top five genes for each scale are presented in Supplemental Table S3.
