The Estonian Genome Project is a biobank coordinated by the University of Tartu (EGPUT)18. The project is conducted according to Estonian Gene Research Act and all participants have given written informed consent. The cohort includes more than 39000 individuals older than 18 years of age and reflects closely the age distribution in the Estonian population (33% male, 67% female; 83% Estonians, 14% Russians, 3% other). Subjects are recruited by general practitioners (GP) and hospital physicians and are then randomly selected. Computer Assisted Personal interview (CAPI) was filled during 1-2 hours at the doctor’s office. The data included personal data (place of birth, place(s) of living, nationality etc.), family history (four generations), educational and occupational history, lifestyle and anthropometric data. 1090 randomly-selected subjects were genotyped using the Illumina 370cnvDuo array, 998 passing the required criteria (nationality, genotyping call rate, phenotype availability).
