Most U.S. adults -- three quarters of men and nearly two thirds of women -- had no history of either internalizing or externalizing psychopathology, the latter excluding alcohol dependence (top panel of Table 1). Among those with some psychopathology, the vast majority had internalizing only (IO), 17.7% of men and 31.3% of women, compared to 3.1% and 0.7%, respectively, for externalizing only (EO) and 4.5% and 2.6% for both internalizing and externalizing (BIE). IO was almost twice as common among women as among men, whereas EO was about four times as common and BIE about twice as common among men (all p<.001). All types of lifetime psychopathology were considerably more prevalent (p<.001) among individuals with DSM-IV lifetime alcohol dependence (middle panel of Table 1) than in the total population. Among lifetime alcoholics, IO continued to be more prevalent among women and EO more prevalent among men (p<.001), but male and female lifetime alcoholics were equally likely to have BIE.