Gender differences in the relationship of internalizing and externalizing psychopathology to alcohol dependence: likelihood, expression and course.

paper Cited Public

Authors: Dawson, Deborah A; Goldstein, Risë B; Moss, Howard B; Li, Ting-Kai; Grant, Bridget F
Year: 2010
Journal: Drug and alcohol dependence
PMID: 20558014
DOI: 10.1016/j.drugalcdep.2010.04.019
PMCID: PMC2953598

#	Section	Preview
0	1. Introduction — 1.1 Comorbidity of alcohol dependence with internalizing and externalizing psychopathology	Numerous studies in general population samples have demonstrated that alcohol dependence is highly…
1	1. Introduction — 1.1 Comorbidity of alcohol dependence with internalizing and externalizing psychopathology	disorders were considerably lower, with OR of 4.1 and 2.6 respectively (Grant et al., 2004a). All of…
2	1. Introduction — 1.1 Comorbidity of alcohol dependence with internalizing and externalizing psychopathology	Longitudinal studies of adolescents have provided rich data on the substantial impact of…
3	1. Introduction — 1.1 Comorbidity of alcohol dependence with internalizing and externalizing psychopathology	Although associations during youth and adolescence between alcohol problems and internalizing…
4	1. Introduction — 1.2 Gender differences in the comorbidity of alcohol dependence with internalizing and externalizing psychopathology	Past studies have reported gender differences in alcoholic subtypes, including an excess of women in…
5	1. Introduction — 1.2 Gender differences in the comorbidity of alcohol dependence with internalizing and externalizing psychopathology	prior mood and anxiety disorders (Kessler et al., 1997). Data on 12-month disorders from the…
6	1. Introduction — 1.3 Associations of internalizing and externalizing psychopathology with expression and course of alcohol dependence	Studies in treatment and population samples have confirmed that alcoholic subtypes marked by…
7	1. Introduction — 1.4 Gender differences in associations of internalizing and externalizing psychopathology with expression and course of alcohol dependence	Few studies have examined gender variation in the association of internalizing and externalizing…
8	1. Introduction — 1.5 Limitations of existing research and goals of present analysis	Much remains to be clarified about the associations of internalizing and externalizing…
9	1. Introduction — 1.5 Limitations of existing research and goals of present analysis	To address these gaps in the literature, this paper uses data from a nationally representative…
10	2. Methods — 2.1 Sample	The data used in this analysis came from Wave 1 of the National Epidemiologic Survey on Alcohol and…
11	2. Methods — 2.1 Sample	United States on socioeconomic variables based on the 2000 Decennial Census. Data were collected in…
12	2. Methods — 2.2 Measurement of DSM-IV alcohol dependence	DSM-IV alcohol dependence (American Psychiatric Association, 1994) was measured using the Alcohol…
13	2. Methods — 2.3 Measurement of externalizing and internalizing psychopathology	Four categories of lifetime psychopathology were considered in this analysis: 1) neither…
14	2. Methods — 2.3 Measurement of externalizing and internalizing psychopathology	All psychiatric disorders were defined in accordance with DSM-IV criteria. Mood and anxiety…
15	2. Methods — 2.4 Measurement of clinical presentation and course of alcohol dependence	All measures were based on self-report. Consumption measures reflected self-identified period of…
16	2. Methods — 2.5 Reliability and validity of measures	AUDADIS-IV alcohol diagnoses have demonstrated good reliability and validity in test-retest and…
17	2. Methods — 2.6 Analysis	Statistical analyses employed SUDAAN software (Research Triangle Institute, 2001) to account for…
18	3. Results — 3.1 Unadjusted associations of lifetime internalizing and externalizing psychopathology with alcohol dependence	Most U.S. adults -- three quarters of men and nearly two thirds of women -- had no history of either…
19	3. Results — 3.1 Unadjusted associations of lifetime internalizing and externalizing psychopathology with alcohol dependence	For both men and women, the prevalence of lifetime alcohol dependence was lowest among individuals…

Name	Type
12-step participation local	phenotype
2000 Decennial Census local	cohort
ADHD	phenotype
adolescents	cohort
adult antisocial behavior	phenotype
adult antisocial behavior not preceded by conduct disorder local	phenotype
affective disorders	phenotype
age at first drink	phenotype
Age at Onset of Dependence local	phenotype
aggression	phenotype
alcohol	phenotype
alcohol dependence	phenotype
alcoholism	phenotype
Alcohol Problems	phenotype
Alcohol treatment	phenotype
Alcohol Use	phenotype
Alcohol Use Disorder	phenotype
alcohol use disorders	phenotype
antisocial personality disorder	phenotype
anxiety	phenotype
Apollonian problem drinkers local	phenotype
attention deficit hyperactivity disorder	phenotype
AUD	phenotype
average daily volume of ethanol intake local	phenotype
axis I disorder	phenotype
Behavioral inhibition/externalizing local	phenotype
Behavioral response to drinking local	phenotype
BIE local	cohort
BIE local	phenotype
Binge Intake (BIE) local	phenotype
Binge/Intoxication Episodes local	phenotype
BIO local	phenotype
bipolar disorder	phenotype
bipolar I disorder	phenotype
bipolar II disorder	phenotype
Both internalizing and externalizing local	phenotype
Carpenter and Hasin 2001 general population sample local	cohort
cocaine	phenotype
Collaborative Studies on the Genetics of Alcoholism	cohort
comorbidity	phenotype
conduct disorder	phenotype
Consumption Level local	phenotype
density of familial alcoholism local	phenotype
Dependence symptoms	phenotype
Developmentally limited alcoholic subtype local	phenotype
Dionysian problem drinkers local	phenotype
drinkers	phenotype
drinking	phenotype
Drinking expectancies local	phenotype
Drinking motivation local	phenotype
drinks per week	phenotype
drug	drug
drug dependence	phenotype
DSM-IV alcohol dependence	phenotype
dysthymia	phenotype
early alcohol use	phenotype
Early- and rapid-onset dependence local	phenotype
Early and rapid onset of alcoholism local	phenotype
early onset	phenotype
Early Onset (EO) local	phenotype
EO local	cohort
Epidemiologic Catchment Area Study local	cohort
episodes of dependence local	phenotype
Epstein et al. 2002 treatment sample local	cohort
ethanol consumption	phenotype
European Study of the Epidemiology of Mental Disorders local	cohort
European Study of the Epidemiology of Mental Disorders (ESEMeD) local	cohort
externalizing behavior	phenotype
externalizing disorders	phenotype
Externalizing only local	phenotype
family history of alcoholism	phenotype
family history positive	phenotype
fear	phenotype
Female alcoholics	phenotype
generalized anxiety disorder	phenotype
general population	cohort
heaviest drinking local	phenotype
heavy drinking	phenotype
Higher dependence screening scores local	phenotype
Higher severity local	phenotype
Higher treatment utilization local	phenotype
human alcoholics	phenotype
illicit drug dependence	phenotype
Infrequent Onset (IO) local	phenotype
internalizing dimension local	phenotype
internalizing disorders	phenotype
Internalizing only local	phenotype
IO local	cohort
Lahmek et al. 2009 treatment sample local	cohort
Largest quantity of drinks local	phenotype
Lifetime alcoholics local	cohort
Lifetime Alcoholics local	cohort
lifetime alcoholism local	phenotype
Lifetime alcohol treatment local	phenotype
lifetime alcohol use	phenotype
lifetime drinkers local	phenotype
lifetime treatment local	phenotype
major depressive disorder	phenotype
Male alcoholics	phenotype
marijuana	phenotype
medical consequences	phenotype
men	cohort
mood disorders	phenotype
Moss et al. 2007 general population sample local	cohort
Multiple Disorders local	phenotype
Multiple Episodes of Dependence local	phenotype
National Comorbidity Survey	cohort
National Comorbidity Survey (NCS) local	cohort
National Epidemiologic Survey on Alcohol and Related Conditions	cohort
NESARC	cohort
NESARC sample local	cohort
nicotine	drug
nicotine dependence	phenotype
NINE local	cohort
NINE local	phenotype
Non-externalizing psychopathology local	phenotype
onset of dependence local	phenotype
Other Psychopathology local	phenotype
panic disorder	phenotype
personality disorders	phenotype
Physical consequences	phenotype
Poor psychological quality of life local	phenotype
Post-Traumatic Stress Disorder	phenotype
psychiatric disorders	phenotype
Psychological Condition local	phenotype
psychological distress	phenotype
psychopathology	phenotype
remission	phenotype
Remission from Dependence local	phenotype
Severe chronic alcoholic subtype local	phenotype
sex	phenotype
social consequences	phenotype
social desirability bias	phenotype
social phobia	phenotype
Somatic Condition local	phenotype
specific phobia	phenotype
substance abuse	phenotype
substance use	phenotype
tobacco use	phenotype
treatment samples	cohort
treatment utilization	phenotype
Twin cohort	cohort
Type A alcoholic patients local	phenotype
Type A alcoholics	phenotype
Type B alcoholic patients local	phenotype
Type B alcoholics	phenotype
United States	cohort
U.S. adults 18 years or older local	cohort
voluntary alcohol consumption	phenotype
Wave 1 NESARC sample local	cohort
Wave 1 remission local	phenotype
wave 2	cohort
Windle and Scheidt 2004 treatment sample local	cohort
women	cohort
Young antisocial alcoholic subtype local	phenotype

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In this knowledge base

Title	Year	PMID
Influence of Parental Alcohol Dependence Symptoms and Parenting on Adolescent Risky Drinking and Conduct Problems: A Family Systems Perspective.	2018	29969154
Directional relationships between alcohol use and antisocial behavior across adolescence.	2014	24930394
Psychiatric comorbidity and perceived alcohol stigma in a nationally representative sample of individuals with DSM-5 alcohol use disorder.	2014	24848495
Gender differences in lifetime alcohol dependence: results from the national epidemiologic survey on alcohol and related conditions.	2013	23763329
Parent, sibling and peer associations with subtypes of psychiatric and substance use disorder comorbidity in offspring.	2013	22921146

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Gender and Alcohol Use Disorders Diagnostic Criteria in Emergency Department Patients of Argentina.	Conde K et al.	—	2016	→
Gender-specific effects of comorbid depression and anxiety on the propensity to drink in negative emotional states.	Karpyak VM et al.	—	2016	→
Associations of prodynorphin sequence variation with alcohol dependence and related traits are phenotype-specific and sex-dependent.	Winham SJ et al.	—	2015	→
Basal anxiety negatively correlates with vulnerability to ethanol-induced behavioral sensitization in DBA/2J mice: modulation by diazepam.	Botia B et al.	—	2015	→
Psychiatric Symptom Clusters as Risk Factors for Alcohol Use Disorders in Adolescence: A National Study.	Harford TC et al.	—	2015	→
Reciprocal Effects of Internalizing and Oppositional Defiance Symptoms on Heavy Drinking and Alcohol-Related Harms in Young Adulthood.	Thompson KD et al.	—	2015	→
Adolescent alcohol use is positively associated with later depression in a population-based U.K. cohort.	Edwards AC et al.	—	2014	→
Alcohol use disorder in women: Risks and consequences of an adolescent onset and persistent course.	Foster KT et al.	—	2014	→
Directional relationships between alcohol use and antisocial behavior across adolescence.	Cho SB et al.	—	2014	→
Gender differences in relationships among PTSD severity, drinking motives, and alcohol use in a comorbid alcohol dependence and PTSD sample.	Lehavot K et al.	—	2014	→
Prenatal drug exposure, behavioral problems, and drug experimentation among African-American urban adolescents.	Wang Y et al.	—	2014	→
Psychiatric comorbidity and perceived alcohol stigma in a nationally representative sample of individuals with DSM-5 alcohol use disorder.	Glass JE et al.	—	2014	→
Sex differences in impulsive action and impulsive choice.	Weafer J et al.	—	2014	→
Understanding the addiction cycle: a complex biology with distinct contributions of genotype vs. sex at each stage.	Wilhelm CJ et al.	—	2014	→
Are addictions diseases or choices?	Leyton M	—	2013	→
Associations between psychosocial problems and personality disorders among Egyptian adolescents.	Elbheiry AE et al.	—	2013	→
Closing the Gender Gap: The Case for Gender-Specific Alcoholism Research.	Ruiz SM et al.	—	2013	→
Gender differences in lifetime alcohol dependence: results from the national epidemiologic survey on alcohol and related conditions.	Khan S et al.	—	2013	→
Parent, sibling and peer associations with subtypes of psychiatric and substance use disorder comorbidity in offspring.	McCutcheon VV et al.	—	2013	→
Predictors of alcohol-related problems among depressed and non-depressed women.	Nolen-Hoeksema S et al.	—	2013	→
Reward-related ventral striatum reactivity mediates gender-specific effects of a galanin remote enhancer haplotype on problem drinking.	Nikolova YS et al.	—	2013	→
An invariant dimensional liability model of gender differences in mental disorder prevalence: evidence from a national sample.	Eaton NR et al.	—	2012	→
Sex differences in prevalence and comorbidity of alcohol and drug use disorders: results from wave 2 of the National Epidemiologic Survey on Alcohol and Related Conditions.	Goldstein RB et al.	—	2012	→
The role of conduct disorder in the association between ADHD and alcohol use (disorder). Results from the Netherlands Mental Health Survey and Incidence Study-2.	Tuithof M et al.	—	2012	→
X chromosome inactivation in women with alcoholism.	Manzardo AM et al.	—	2012	→
OPRM1 gene variation influences hypothalamic-pituitary-adrenal axis function in response to a variety of stressors in rhesus macaques.	Schwandt ML et al.	—	2011	→
Gender differences in generalized anxiety disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC).	Vesga-López O et al.	—	2008	→