Lifetime co-occurrence of DSM-III-R alcohol abuse and dependence with other psychiatric disorders in the National Comorbidity Survey.
paper
Cited
Public
Unavailable
- Authors
- Kessler, R C; Crum, R M; Warner, L A; Nelson, C B; Schulenberg, J; Anthony, J C
- Year
- 1997
- Journal
- Archives of general psychiatry
- PMID
- 9107147
- DOI
- 10.1001/archpsyc.1997.01830160031005
OBJECTIVE: To study patterns of co-occurrence of lifetime DSM-III-R alcohol disorders in a household sample. METHODS: Data came from the National Comorbidity Survey (NCS), a nationally representative household survey. Diagnoses were based on a modified version of the Composite International Diagnostic Interview. RESULTS: Respondents with lifetime NCS/DSM-III-R alcohol abuse or dependence had a high probability of carrying at least 1 other lifetime NCS/DSM-III-R diagnosis. Retrospective reports have suggested that most lifetime co-occurring alcohol disorders begin at a later age than at least 1 other NCS/DSM-III-R disorder. Earlier disorders are generally stronger predictors of alcohol dependence than alcohol abuse and stronger among women than men. Lifetime co-occurrence is positively, but weakly, associated with the persistence of alcohol abuse among men and of alcohol dependence among both men and women. CONCLUSIONS: Caution is needed in interpreting the results due to the fact that diagnoses were made by nonclinicians and results are based on retrospective reports of the age at onset. Within the context of these limitations, though, these results show that alcohol abuse and dependence are often associated with other lifetime DSM-III-R disorders and suggest that, at least in recent cohorts, the alcohol use disorders are usually temporally secondary. Prospective data and data based on clinically confirmed diagnoses are needed to verify these findings.
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| Polymorphisms in the GAD2 gene-region are associated with susceptibility for unipolar depression and with a risk factor for anxiety disorders. | Unschuld PG et al. | — | 2009 | → |
| Predictors of illicit substance dependence among individuals with alcohol dependence. | Sintov ND et al. | — | 2009 | → |
| Predictors of nonadherence among individuals with bipolar disorder receiving treatment in a community mental health clinic. | Sajatovic M et al. | — | 2009 | → |
| Predictors of psychological morbidity in liver transplant assessment candidates: is alcohol abuse or dependence a factor? | Day E et al. | — | 2009 | → |
| Psychiatric comorbidities and schizophrenia. | Buckley PF et al. | — | 2009 | → |
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| Serum levels of brain-derived neurotrophic factor in comorbidity of depression and alcohol dependence. | Umene-Nakano W et al. | — | 2009 | → |
| Sex differences in drug-related stress-system changes: implications for treatment in substance-abusing women. | Fox HC et al. | — | 2009 | → |
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| Two types of classification in female alcoholism. | Traber R et al. | — | 2009 | → |
| Understanding social anxiety as a risk for alcohol use disorders: fear of scrutiny, not social interaction fears, prospectively predicts alcohol use disorders. | Buckner JD et al. | — | 2009 | → |
| Age- and sex-dependent effects of footshock stress on subsequent alcohol drinking and acoustic startle behavior in mice selectively bred for high-alcohol preference. | Chester JA et al. | — | 2008 | → |
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| Counselor and client characteristics in mental health versus substance abuse treatment settings providing services for co-occurring disorders. | Mangrum LF et al. | — | 2008 | → |
| Depressed mood in childhood and subsequent alcohol use through adolescence and young adulthood. | Crum RM et al. | — | 2008 | → |
| Desipramine blocks alcohol-induced anxiety- and depressive-like behaviors in two rat strains. | Getachew B et al. | — | 2008 | → |
| Differences in help seeking rates after brief intervention for alcohol use disorders in general practice patients with and without comorbid anxiety or depressive disorders. | Grothues JM et al. | — | 2008 | → |
| Drinking motives as mediators in the relation between personality disorder symptoms and alcohol use disorder. | Tragesser SL et al. | — | 2008 | → |
| Effectiveness of brief alcohol interventions for general practice patients with problematic drinking behavior and comorbid anxiety or depressive disorders. | Grothues JM et al. | — | 2008 | → |
| Elevated rates of substance use disorders in non-psychotic siblings of individuals with schizophrenia. | Smith MJ et al. | — | 2008 | → |
| Estimating co-occurring behavioral trajectories within a neighborhood context: a case study of multivariate transition models for clustered data. | Cerdá M et al. | — | 2008 | → |
| Externalizing disorders in American Indians: comorbidity and a genome wide linkage analysis. | Ehlers CL et al. | — | 2008 | → |
| Gender differences in generalized anxiety disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). | Vesga-López O et al. | — | 2008 | → |
| Gender differences in social influences and stressors linked to increased drinking. | Lemke S et al. | — | 2008 | → |
| Gender sensitivity among general practitioners: results of a training programme. | Celik HH et al. | — | 2008 | → |
| Genetic approaches to addiction: genes and alcohol. | Ducci F et al. | — | 2008 | → |
| Genetic association of DRD2 polymorphisms with anxiety scores among alcohol-dependent patients. | Joe KH et al. | — | 2008 | → |
| Guideline-concordant hepatitis C virus testing and notification among patients with and without mental disorders. | Kilbourne AM et al. | — | 2008 | → |
| Impact of remitted substance use disorders on the future course of bipolar I disorder: findings from a clinical trial. | Gaudiano BA et al. | — | 2008 | → |
| Implications of cannabis use and heavy alcohol use on HIV drug risk behaviors in Russian heroin users. | Walley AY et al. | — | 2008 | → |
| Implications of comorbid alcohol dependence among individuals with social anxiety disorder. | Buckner JD et al. | — | 2008 | → |
| Influence of trait anxiety on inhibitory control in alcohol-dependent patients: simultaneous acquisition of ERPs and BOLD responses. | Karch S et al. | — | 2008 | → |
| Is depressed mood in childhood associated with an increased risk for initiation of alcohol use during early adolescence? | Crum RM et al. | — | 2008 | → |
| Levetiracetam for the treatment of co-occurring alcohol dependence and anxiety: case series and review. | Mariani JJ et al. | — | 2008 | → |
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| Medical and substance-related comorbidity in bipolar disorder: translational research and treatment opportunities. | McIntyre RS et al. | — | 2008 | → |
| Mortality associated with depression: a forty-year perspective from the Stirling County Study. | Murphy JM et al. | — | 2008 | → |
| Motivation and the stages of change among individuals with severe mental illness and substance abuse disorders. | DiClemente CC et al. | — | 2008 | → |
| Naltrexone is associated with reduced drinking by alcohol dependent patients receiving antidepressants for mood and anxiety symptoms: results from VA Cooperative Study No. 425, "Naltrexone in the treatment of alcoholism". | Krystal JH et al. | — | 2008 | → |
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| Neurobiology of addiction. An integrative review. | Goodman A | — | 2008 | → |
| Nine-year follow-up of panic disorder in chest pain patients: clinical course and predictors of outcome. | Bringager CB et al. | — | 2008 | → |
| Nonfearful panic disorder in chest-pain patients: status after nine-year follow-up. | Bringager CB et al. | — | 2008 | → |
| Ordered subsets linkage analysis of antisocial behavior in substance use disorder among participants in the Collaborative Study on the Genetics of Alcoholism. | Jacobson KC et al. | — | 2008 | → |
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| Pathways to suicidality across ethnic groups in Canadian adults: the possible role of social stress. | Clarke DE et al. | — | 2008 | → |
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| Prevalence and comorbidity of major internalizing and externalizing problems among adolescents and adults presenting to substance abuse treatment. | Chan YF et al. | — | 2008 | → |
| Prevalence of co-occurring substance use and other mental disorders in the Canadian population. | Rush B et al. | — | 2008 | → |
| Promoting continuing care adherence among substance abusers with co-occurring psychiatric disorders following residential treatment. | DeMarce JM et al. | — | 2008 | → |
| Prospective associations between cannabis use, abuse, and dependence and panic attacks and disorder. | Zvolensky MJ et al. | — | 2008 | → |
| Proton magnetic resonance spectroscopy in alcohol use disorders: a potential new endophenotype? | Meyerhoff DJ et al. | — | 2008 | → |
| Psychiatric comorbidity in older long-term abstinent alcoholics. | Fein G et al. | — | 2008 | → |
| Self-reported health functioning in Swedish alcohol-dependent individuals: age and gender perspectives. | Berglund K et al. | — | 2008 | → |
| Serotonergic responses in depressed patients with or without a history of alcohol use disorders and healthy controls. | Sher L et al. | — | 2008 | → |
| Sex differences in depression symptoms in treatment-seeking adults: confirmatory analyses from the Sequenced Treatment Alternatives to Relieve Depression study. | Marcus SM et al. | — | 2008 | → |
| Specificity of social anxiety disorder as a risk factor for alcohol and cannabis dependence. | Buckner JD et al. | — | 2008 | → |
| Spirituality and health: empirically based reflections on recovery. | Pearce MJ et al. | — | 2008 | → |
| Striatal sensitivity to reward deliveries and omissions in substance dependent patients. | Bjork JM et al. | — | 2008 | → |
| Substance use and sexual risk within the context of gender inequality in South Africa. | Wechsberg WM et al. | — | 2008 | → |
| Temperament and character traits in patients with bipolar disorder and associations with comorbid alcoholism or anxiety disorders. | Nery FG et al. | — | 2008 | → |
| The association of depression and anxiety with obesity and unhealthy behaviors among community-dwelling US adults. | Strine TW et al. | — | 2008 | → |
| The effectiveness of antipsychotic medications in patients who use or avoid illicit substances: results from the CATIE study. | Swartz MS et al. | — | 2008 | → |
| The impact of alcoholics anonymous on other substance abuse-related twelve-step programs. | Laudet AB | — | 2008 | → |
| The interaction of co-occurring mental disorders and recovery management checkups on substance abuse treatment participation and recovery. | Rush BR et al. | — | 2008 | → |
| The role of selected factors in the development and consequences of alcohol dependence. | Gilbertson R et al. | — | 2008 | → |
| Treatment-naive active alcoholics have greater psychiatric comorbidity than normal controls but less than treated abstinent alcoholics. | Di Sclafani V et al. | — | 2008 | → |
| Treatment of alcohol dependence in patients with co-morbid major depressive disorder--predictors for the outcomes with memantine and escitalopram medication. | Muhonen LH et al. | — | 2008 | → |
| World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Substance Use and Related Disorders, Part 1: Alcoholism. | Soyka M et al. | — | 2008 | → |
| A co-morbidity of alcohol dependence with other psychiatric disorders in young adult Mexican Americans. | Gilder DA et al. | — | 2007 | → |
| Age of first marijuana use and the occurrence of marijuana use disorders in Southwest California Indians. | Ehlers CL et al. | — | 2007 | → |
| Alcohol use disorders and the use of treatment services among college-age young adults. | Wu LT et al. | — | 2007 | → |
| Antisocial behavioral syndromes and DSM-IV alcohol use disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. | Goldstein RB et al. | — | 2007 | → |
| A perfect platform: combining contingency management with medications for drug abuse. | Carroll KM et al. | — | 2007 | → |
| A randomized trial of a DWI intervention program for first offenders: intervention outcomes and interactions with antisocial personality disorder among a primarily American-Indian sample. | Woodall WG et al. | — | 2007 | → |
| Attention-deficit/hyperactivity disorder risk for heavy drinking and alcohol use disorder is age specific. | Molina BS et al. | — | 2007 | → |
| Attention problems among children with a positive family history of alcohol abuse or dependence and controls. Prevalence and course for the period from preteen to early teen years. | Barnow S et al. | — | 2007 | → |
| Baclofen for alcoholism. | Garbutt JC et al. | — | 2007 | → |
| Childhood physical and sexual abuse and lifetime number of suicide attempts: a persistent and theoretically important relationship. | Joiner TE et al. | — | 2007 | → |
| Comorbid substance and mental disorders among rural Americans: results from the National Comorbidity Survey. | Simmons LA et al. | — | 2007 | → |
| Comparison of self-reports and biological measures for alcohol, tobacco, and illicit drugs consumption in psychiatric inpatients. | de Beaurepaire R et al. | — | 2007 | → |
| Concurrent and predictive validity of drug use and psychiatric diagnosis among first-time DWI offenders. | Palmer RS et al. | — | 2007 | → |
| Convergent validity of the Timeline Followback for persons with comorbid psychiatric disorders engaged in residential substance use treatment. | DeMarce JM et al. | — | 2007 | → |
| Correlates of "non-problematic" and "problematic" substance use among depressed adolescents in primary care. | Goldstein RB et al. | — | 2007 | → |
| Decision making and binge drinking: a longitudinal study. | Goudriaan AE et al. | — | 2007 | → |
| Depression and social phobia secondary to alcohol dependence. | Olgiati P et al. | — | 2007 | → |
| Development and initial validation of the Worry-Reduction Alcohol Expectancy Scale. | Smith JP et al. | — | 2007 | → |
| Does the association between alcohol consumption and depression depend on how they are measured? | Graham K et al. | — | 2007 | → |
| DSM-V research agenda: substance abuse/psychosis comorbidity. | Rounsaville BJ | — | 2007 | → |
| Evaluating personal alcohol feedback as a selective prevention for college students with depressed mood. | Geisner IM et al. | — | 2007 | → |
| Family history of psychiatric disorders and alcohol and substance misuse in patients with bipolar I disorder, substance use disorder, or both. | Sbrana A et al. | — | 2007 | → |
| Feasibility and acceptability of a mental health screening tool and training programme in the youth alcohol and other drug (AOD) sector. | Hides L et al. | — | 2007 | → |
| First-degree relative history of alcoholism in eating disorder inpatients: relationship to eating and substance use psychopathology. | Redgrave GW et al. | — | 2007 | → |
| Gene-environment interactions in addictive disorders: epidemiological and methodological aspects. | Gorwood P et al. | — | 2007 | → |
| Genetic correlation between innate alcohol preference and fear-potentiated startle in selected mouse lines. | Barrenha GD et al. | — | 2007 | → |
| High and low dosage oxcarbazepine versus naltrexone for the prevention of relapse in alcohol-dependent patients. | Martinotti G et al. | — | 2007 | → |
| Increased anxiety and other similarities in temperament of alcoholics with and without antisocial personality disorder across three diverse populations. | Ducci F et al. | — | 2007 | → |
| Increased suicidality in mania complicated by alcoholism. | Fan AH et al. | — | 2007 | → |
| Influence of anxiety on electrophysiological correlates of response inhibition capacities in alcoholism. | Karch S et al. | — | 2007 | → |
| Internalizing and externalizing subtypes in female sexual assault survivors: implications for the understanding of complex PTSD. | Miller MW et al. | — | 2007 | → |
| Management of persons with co-occurring severe mental illness and substance use disorder: program implications. | Drake RE et al. | — | 2007 | → |
| Marital and family processes in the context of alcohol use and alcohol disorders. | Leonard KE et al. | — | 2007 | → |
| Melancholia and atypical depression in the Zurich study: epidemiology, clinical characteristics, course, comorbidity and personality. | Angst J et al. | — | 2007 | → |
| Methamphetamine use by incarcerated women: comorbid mood and anxiety problems. | Vik PW | — | 2007 | → |
| Naltrexone and cognitive behavioral coping skills therapy for the treatment of alcohol drinking and eating disorder features in alcohol-dependent women: a randomized controlled trial. | O'Malley SS et al. | — | 2007 | → |
| Only male mice show sensitization of handling-induced convulsions across repeated ethanol withdrawal cycles. | Veatch LM et al. | — | 2007 | → |
| Origin of the comorbidity of anxiety disorders and alcohol dependence: findings of a general population study. | Marquenie LA et al. | — | 2007 | → |
| Outpatient Long-term Intensive Therapy for Alcoholics (OLITA): a successful biopsychosocial approach to the treatment of alcoholism. | Krampe H et al. | — | 2007 | → |
| P3 components and adolescent binge drinking in Southwest California Indians. | Ehlers CL et al. | — | 2007 | → |
| Panic disorder, trait anxiety, and alcohol use in pregnant and nonpregnant women. | Meshberg-Cohen S et al. | — | 2007 | → |
| Personality disorder symptoms, drinking motives, and alcohol use and consequences: cross-sectional and prospective mediation. | Tragesser SL et al. | — | 2007 | → |
| Pharmacotherapy for schizophrenia and co-occurring substance use disorders. | Green AI | — | 2007 | → |
| Positron emission tomography study of regional brain metabolic responses to a serotonergic challenge in major depressive disorder with and without comorbid lifetime alcohol dependence. | Sher L et al. | — | 2007 | → |
| Prevalence of heroin and methamphetamine male users in the northern Taiwan, 1999-2002: capture-recapture estimates. | Chiang SC et al. | — | 2007 | → |
| Psychiatric comorbidity in long-term abstinent alcoholic individuals. | Di Sclafani V et al. | — | 2007 | → |
| Psychiatric symptomatology among individuals in alcohol detoxification treatment. | Johnson ME et al. | — | 2007 | → |
| Racial and ethnic disparities in SSRI availability in substance abuse treatment. | Knudsen HK et al. | — | 2007 | → |
| Reasons for increased substance use in psychosis. | Gregg L et al. | — | 2007 | → |
| Recognition and management of depression in a substance use disorder treatment population. | Curran GM et al. | — | 2007 | → |
| Relationships between anxiety and externalizing disorders in youth: the influences of age and gender. | Marmorstein NR | — | 2007 | → |
| Should impaired liver function be held responsible for cognitive impairment and poor health-related quality of life in alcoholic cirrhosis? | Paparrigopoulos T et al. | — | 2007 | → |
| SSRIs and birth defects. | Kelly MB et al. | — | 2007 | → |
| Sub-diagnostic psychiatric comorbidity in alcoholics. | Fein G et al. | — | 2007 | → |
| The impact of gender, depression, and personality on craving. | Zilberman ML et al. | — | 2007 | → |
| The influence of parental drinking behaviour and antisocial personality disorder on adolescent behavioural problems: results of the Greifswalder Family Study. | Barnow S et al. | — | 2007 | → |
| The role of childhood risk factors in initiation of alcohol use and progression to alcohol dependence. | Sartor CE et al. | — | 2007 | → |
| The role of conduct disorder in explaining the comorbidity between alcohol and illicit drug dependence in adolescence. | Button TM et al. | — | 2007 | → |
| The spectrum of substance abuse in bipolar disorder: reasons for use, sensation seeking and substance sensitivity. | Bizzarri JV et al. | — | 2007 | → |
| Women, aging, and alcohol use disorders. | Epstein EE et al. | — | 2007 | → |
| Age at first intoxication and alcohol use disorders in Southwest California Indians. | Ehlers CL et al. | — | 2006 | → |
| Alcoholism and suicidal behavior: a clinical overview. | Sher L | — | 2006 | → |
| Alcohol use, alcohol problems, and depressive symptomatology among newly married couples. | Homish GG et al. | — | 2006 | → |
| Alcohol use and misuse in urban Mexican men and women: an epidemiologic perspective. | Slone LB et al. | — | 2006 | → |
| Availability of integrated care for co-occurring substance abuse and psychiatric conditions. | Ducharme LJ et al. | — | 2006 | → |
| Bipolar disorder and comorbid alcoholism: prevalence rate and treatment considerations. | Frye MA et al. | — | 2006 | → |
| Challenges in genetic studies of the etiology of substance use and substance use disorders: introduction to the special issue. | Prescott CA et al. | — | 2006 | → |
| Childhood depressive symptoms and early onset of alcohol use. | Wu P et al. | — | 2006 | → |
| Comorbidity between alcohol dependence and illicit drug dependence in adolescents with antisocial behavior and matched controls. | Rhee SH et al. | — | 2006 | → |
| Comorbidity between substance use disorders and psychiatric conditions. | Schuckit MA | — | 2006 | → |
| Comorbidity of substance use with depression and other mental disorders: from Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) to DSM-V. | Nunes EV et al. | — | 2006 | → |
| Correlates of alcohol use among anxious and depressed primary care patients. | Arch JJ et al. | — | 2006 | → |
| Correlation of liver dysfunction biological markers to the mood status of alcohol-dependent individuals. | Liappas IA et al. | — | 2006 | → |
| Currently active and remitted alcohol dependence in a nationwide adult general population--results from the Finnish Health 2000 study. | Pirkola SP et al. | — | 2006 | → |
| Depression amongst Nigerian university students. Prevalence and sociodemographic correlates. | Adewuya AO et al. | — | 2006 | → |
| Diagnosis of comorbid psychiatric disorders in substance users assessed with the Psychiatric Research Interview for Substance and Mental Disorders for DSM-IV. | Hasin D et al. | — | 2006 | → |
| Does co-occurring social phobia interfere with alcoholism treatment adherence and relapse? | Terra MB et al. | — | 2006 | → |
| Educational achievement and early school behavior as predictors of alcohol-use disorders: 35-year follow-up of the Woodlawn Study. | Crum RM et al. | — | 2006 | → |
| Gender differences in alcohol and substance use relapse. | Walitzer KS et al. | — | 2006 | → |
| Gender differences in the relationship between alcohol use and anxiety symptoms among Nigerian college students. | Adewuya AO et al. | — | 2006 | → |
| Illicit drug use and anxiety disorders: findings from two community surveys. | Sareen J et al. | — | 2006 | → |
| Impact of practitioner's training in the management of alcohol dependence: a quasi-experimental 18-month follow-up study. | Malet L et al. | — | 2006 | → |
| Is the association of alcohol use disorders with major depressive disorder a consequence of undiagnosed bipolar-II disorder? | Angst J et al. | — | 2006 | → |
| Is there heterogeneity among syndromes of substance use disorder for illicit drugs? | Beseler C et al. | — | 2006 | → |
| "I thought there was no hope for me": a behavioral intervention for urban mothers with problem drinking. | de Guzman R et al. | — | 2006 | → |
| Lifetime psychiatric comorbidity with substance use disorders: does healthcare use modify the strength of associations ? | Encrenaz G et al. | — | 2006 | → |
| Links between depression and substance abuse in adolescents: neurobiological mechanisms. | Rao U | — | 2006 | → |
| Major depression and immunity in alcohol-dependent persons. | Schleifer SJ et al. | — | 2006 | → |
| Mental health and alcohol, drugs and tobacco: a review of the comorbidity between mental disorders and the use of alcohol, tobacco and illicit drugs. | Jané-Llopis E et al. | — | 2006 | → |
| New pharmacological approaches for the treatment of alcoholism. | Soyka M et al. | — | 2006 | → |
| Nicotine dependence, use of illegal drugs and psychiatric morbidity. | Martínez-Ortega JM et al. | — | 2006 | → |
| Overlap of clusters of psychiatric symptoms among clients of a comprehensive addiction treatment service. | Castel S et al. | — | 2006 | → |
| P300 amplitude as an indicator of externalizing in adolescent males. | Patrick CJ et al. | — | 2006 | → |
| Peer influence and gender differences in problematic cannabis use among individuals with social anxiety. | Buckner JD et al. | — | 2006 | → |
| Pharmacotherapy of alcoholism in patients with co-morbid psychiatric disorders. | Goldstein BI et al. | — | 2006 | → |
| Prevalence of major depressive disorder in Nigerian college students with alcohol-related problems. | Adewuya AO | — | 2006 | → |
| Psychiatric comorbidity and progression in drug use in adult male twins: implications for the design of genetic association studies. | Todorov AA et al. | — | 2006 | → |
| Psychoactive drug abuse in older adults. | Simoni-Wastila L et al. | — | 2006 | → |
| Relapse to alcohol and drug use among individuals diagnosed with co-occurring mental health and substance use disorders: a review. | Bradizza CM et al. | — | 2006 | → |
| Relationships among the level of response to alcohol and the number of alcoholic relatives in predicting alcohol-related outcomes. | Schuckit M et al. | — | 2006 | → |
| Severity of dependence and motivation for treatment: comparison of marijuana- and cocaine-dependent treatment seekers. | Levin FR et al. | — | 2006 | → |
| Sleep architecture in homicidal women with antisocial personality disorder--a preliminary study. | Lindberg N et al. | — | 2006 | → |
| Social anxiety and problematic alcohol consumption: the mediating role of drinking motives and situations. | Buckner JD et al. | — | 2006 | → |
| Social anxiety and problematic cannabis use: evaluating the moderating role of stress reactivity and perceived coping. | Buckner JD et al. | — | 2006 | → |
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