Gender differences in lifetime alcohol dependence: results from the national epidemiologic survey on alcohol and related conditions.
paper
Cited
Public
- Authors
- Khan, Sharaf; Okuda, Mayumi; Hasin, Deborah S; Secades-Villa, Roberto; Keyes, Katherine; Lin, Keng-Han; Grant, Bridget; Blanco, Carlos
- Year
- 2013
- Journal
- Alcoholism, clinical and experimental research
- PMID
- 23763329
- DOI
- 10.1111/acer.12158
- PMCID
- PMC3796956
BACKGROUND: An extensive clinical literature has noted gender differences in the etiology and clinical characteristics of individuals with alcohol dependence (AD). Despite this knowledge, many important questions remain. METHODS: Using the 2001 to 2002 National Epidemiologic Survey on Alcohol and Related Conditions (n = 43,093), we examined differences in sociodemographic characteristics, psychiatric and medical comorbidities, clinical correlates, risk factors, and treatment-utilization patterns of men (N = 2,974) and women (N = 1,807) with lifetime AD. RESULTS: Men with lifetime AD were more likely than women to be diagnosed with any substance use disorder and antisocial personality disorder, whereas women were more likely to have mood and anxiety disorders. After adjusting for sociodemographic characteristics and gender differences in psychiatric comorbidity in the general population, AD was associated with externalizing disorders and any mood disorder among women only. Men with AD met more criteria, had longer episodes, and were younger at the age of first drink. There were no gender differences in remission rates. Women with AD were more likely to have a family and a spouse with history of alcohol use disorders. Treatment rates were low for both genders, and women were more likely to report social stigmatization as a treatment barrier. CONCLUSIONS: There are important gender differences in the psychiatric comorbidities, risk factors, clinical characteristics, and treatment-utilization patterns among individuals with lifetime AD.
Lifetime prevalence of nicotine dependence and drug abuse in men and women with and without alcohol dependence.
Lifetime prevalence of pathological gambling, conduct disorder, and any mood disorder in men and women with and without alcohol dependence.
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| Title | Year | PMID |
|---|---|---|
| Association of substance dependence phenotypes in the COGA sample. | 2015 | 24832863 |
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Sex and gender in alcohol use disorder and alcohol-associated liver disease in the United States: A narrative review. | Carlini LE et al. | β | 2026 | β |
| Alcohol and alcoholism associated neurological disorders: Current updates in a global perspective and recent recommendations. | Sahu P et al. | β | 2025 | β |
| Caregiver-Patient Dynamics in Alcohol Use Disorders: A Cross-Sectional Study. | Ignat LA et al. | β | 2025 | β |
| Chronic pain increases sensitivity to pain-induced reinstatement of ethanol seeking in male mice | Nothem MA et al. | β | 2025 | β |
| Chronic pain increases sensitivity to pain-induced reinstatement of ethanol seeking in male mice. | Nothem MA et al. | β | 2025 | β |
| Empirical Derivation and Prediction of Treatment Trajectories in Harmonized AUD Clinical Trial Datasets. | Kohler RJ et al. | β | 2025 | β |
| Gender differences in alcohol use disorder treatment: sociodemographic, mental health, personality, and neuropsychological factors. | HΓΈiland K et al. | β | 2025 | β |
| Latent Classes of Comorbid Substance Use and Internalizing and Externalizing Symptoms and Their Stability in U.S. Adults Over Time: Findings from the PATH Study Waves 1-3 (2013-2016). | Blondino CT et al. | β | 2025 | β |
| Postdeployment At-Risk Drinking Among Active Duty Women: Health Care Utilization and Military Readiness Outcomes. | Adams RS et al. | β | 2025 | β |
| Sex and gender differences in co-occurring substance use and depressive disorders: a systematic review. | Grant P et al. | β | 2025 | β |
| Treatment rates and delays for mental and substance use disorders: results from the Australian National Survey of Mental Health and Wellbeing. | Birrell L et al. | β | 2025 | β |
| Unraveling Dual Cognitive Disorders: A Case Report and Literature Review on Marchiafava-Bignami Disease and Possible Alzheimer's Disease. | Iliuta FP et al. | β | 2025 | β |
| U.S. Jails and fatal drug overdoses: patterns, predictors and the role of rehabilitative contexts. | St John V et al. | β | 2025 | β |
| Women and men veterans' initiation, engagement, and retention in treatment for substance use disorders: A cross-sectional investigation using VHA administrative data. | Simpson TL et al. | β | 2025 | β |
| Alcohol Use Disorder Polygenic Score Compared With Family History and ADH1B. | Lai D et al. | β | 2024 | β |
| Association patterns of antisocial personality disorder across substance use disorders. | Low A et al. | β | 2024 | β |
| Neurological Disorders Induced by Drug Use: Effects of Adolescent and Embryonic Drug Exposure on Behavioral Neurodevelopment. | Karatayev O et al. | β | 2024 | β |
| Retracted: Gender Differences in Alcohol Treatment. | Blendberg JM et al. | β | 2024 | β |
| Sex-Specific Association of Alcohol Use Disorder With Suicide Mortality: A Systematic Review and Meta-Analysis. | Lange S et al. | β | 2024 | β |
| The Developmental Trajectory to Cannabis Use Disorder. | Hinckley JD et al. | β | 2024 | β |
| A cohort study examining changes in treatment patterns for alcohol use disorder among commercially insured adults in the United States during the COVID-19 pandemic. | Busch AB et al. | β | 2023 | β |
| Are Cisgender Women and Transgender and Nonbinary People Drinking More During the COVID-19 Pandemic? It Depends. | Veldhuis CB et al. | β | 2023 | β |
| Chronic exposure to inhaled vaporized cannabis high in Ξ9-THC alters brain structure in adult female mice. | Taylor A et al. | β | 2023 | β |
| Developmental trajectories of alcohol and cannabis concurrent use in a nationally representative sample of United States youths. | Roberts W et al. | β | 2023 | β |
| Diagnosis and Management of Marchiafava-Bignami Disease, a Rare Neurological Complication of Long-term Alcohol Abuse. | Singer E et al. | β | 2023 | β |
| Directional associations between posttraumatic stress disorder symptoms and cannabis use in young adults: Uncovering variation by sex, race, and ethnicity. | Davis JP et al. | β | 2023 | β |
| Integration of pharmacotherapy for alcohol use disorder treatment in primary care settings: A scoping review. | Hyland CJ et al. | β | 2023 | β |
| Polygenic risk score for problematic alcohol use predicts heavy drinking and alcohol use disorder symptoms in young adulthood after accounting for adolescent alcohol use and parental alcohol use disorder. | Wang FL et al. | β | 2023 | β |
| Psychological Distress and Heavy Alcohol Consumption Among U.S. Young Women During the COVID-19 Pandemic. | Hahm HC et al. | β | 2023 | β |
| Substance use disorders: a comprehensive update of classification, epidemiology, neurobiology, clinical aspects, treatment and prevention. | Volkow ND et al. | β | 2023 | β |
| Alcohol Use and Misuse Among Chinese Psychiatrists During the Early COVID-19 Pandemic. | Mo D et al. | β | 2022 | β |
| Alcohol use and the gender-specific risk of suicidal behavior: a systematic review and meta-analysis protocol. | Lange S et al. | β | 2022 | β |
| A longitudinal cross-sectional analysis of substance use treatment trends for individuals experiencing homelessness, criminal justice involvement, both, or neither - United States, 2006-2018. | Shearer RD et al. | β | 2022 | β |
| A network approach to substance use, internalizing, and externalizing comorbidity in U.S. adults. | Blondino CT et al. | β | 2022 | β |
| Evaluating risk for alcohol use disorder: Polygenic risk scores and family history. | Lai D et al. | β | 2022 | β |
| Growing alcohol use preceding death by suicide among women compared with men: age-specific temporal trends, 2003-18. | Lange S et al. | β | 2022 | β |
| The indirect effect of negative emotionality via alcohol craving on abstinence self-efficacy among women in alcohol treatment. | Altman BR et al. | β | 2022 | β |
| The role of mood disorders in the progression of and recovery from alcohol and drug use problems: A latent transition analysis. | Crum RM et al. | β | 2022 | β |
| Differences in mental health symptom severity and care engagement among transgender and gender diverse individuals: Findings from a large community health center. | Stanton AM et al. | β | 2021 | β |
| Effects of a selective long-acting amylin receptor agonist on alcohol consumption, food intake and body weight in male and female rats. | Kalafateli AL et al. | β | 2021 | β |
| Gender Differences among Sardinians with Alcohol Use Disorder. | Agabio R et al. | β | 2021 | β |
| Increased mood disorder symptoms, perceived stress, and alcohol use among college students during the COVID-19 pandemic. | Charles NE et al. | β | 2021 | β |
| Mental Health and Substance Use Diagnoses and Treatment Disparities by Sexual Orientation and Gender in a Community Health Center Sample. | Batchelder AW et al. | β | 2021 | β |
| Sex-specific associations between subcortical morphometry in childhood and adult alcohol consumption: A 17-year follow-up study. | Mankiw C et al. | β | 2021 | β |
| The World Health Organization Risk Drinking Levels Measure of Alcohol Consumption: Prevalence and Health Correlates in Nationally Representative Surveys of U.S. Adults, 2001-2002 and 2012-2013. | Shmulewitz D et al. | β | 2021 | β |
| Understanding low treatment seeking rates for alcohol use disorder: A narrative review of the literature and opportunities for improvement. | Venegas A et al. | β | 2021 | β |
| Alcohol and Pain: A Translational Review of Preclinical and Clinical Findings to Inform Future Treatment Strategies. | Edwards S et al. | β | 2020 | β |
| Effects of an Orexin-2 Receptor Antagonist on Sleep and Event-Related Oscillations in Female Rats Exposed to Chronic Intermittent Ethanol During Adolescence. | Amodeo LR et al. | β | 2020 | β |
| Exploring African-American womens' experiences with substance use treatment: A review of the literature. | Redmond ML et al. | β | 2020 | β |
| Sex and Gender Effects in Recovery From Alcohol Use Disorder. | Holzhauer CG et al. | β | 2020 | β |
| Sex differences in incidence and psychiatric comorbidity for alcohol dependence in patients with panic disorder. | Chang HM et al. | β | 2020 | β |
| The relationship between perceived stress and depression in substance use disorder treatment. | McHugh RK et al. | β | 2020 | β |
| Treatment Interventions for Women With Alcohol Use Disorder. | McCrady BS et al. | β | 2020 | β |
| Affective vulnerability in substance use disorders. | McHugh RK et al. | β | 2019 | β |
| Alcohol Use Disorder and Depressive Disorders. | McHugh RK et al. | β | 2019 | β |
| Alcohol use disorder relapse factors: A systematic review. | Sliedrecht W et al. | β | 2019 | β |
| Anxiety and depression in alcohol use disorder individuals: the role of personality and coping strategies. | Ribadier A et al. | β | 2019 | β |
| Associations among interpretation bias, craving, and abstinence self-efficacy in adults with substance use disorders. | Beard C et al. | β | 2019 | β |
| Gender Disparities in Alcohol Use Disorder Treatment Among Privately Insured Patients with Alcohol-Associated Cirrhosis. | Mellinger JL et al. | β | 2019 | β |
| Individual gender and group gender composition as predictors of differential benefit from mindfulness-based relapse prevention for substance use disorders. | Roos C et al. | β | 2019 | β |
| Cerebral white matter sex dimorphism in alcoholism: a diffusion tensor imaging study. | Sawyer KS et al. | β | 2018 | β |
| Characterizing Anxiety Among Individuals Receiving Treatment for Alcohol and Substance Use Disorders. | Domenico LH et al. | β | 2018 | β |
| Sex and gender differences in substance use disorders. | McHugh RK et al. | β | 2018 | β |
| Baseline health status and quality of life after alcohol treatment for women with alcohol dependence. | Bold KW et al. | β | 2017 | β |
| Parent-Offspring Resemblance for Drinking Behaviors in a Longitudinal Twin Sample. | Saunders GR et al. | β | 2017 | β |
| Parents' adverse childhood experiences and mental health screening using home visiting programs: A pilot study. | Johnson K et al. | β | 2017 | β |
| Sex differences in the behavioral sequelae of chronic ethanol exposure. | Jury NJ et al. | β | 2017 | β |
| The Occupy Central (Umbrella) movement and mental health distress in the Hong Kong general public: political movements and concerns as potential structural risk factors of population mental health. | Lau JTF et al. | β | 2017 | β |
| Birth cohort trends in the global epidemiology of alcohol use and alcohol-related harms in men and women: systematic review and metaregression. | Slade T et al. | β | 2016 | β |
| Genetic overlap between impulsivity and alcohol dependence: a large-scale national twin study. | Khemiri L et al. | β | 2016 | β |
| Mental disorders and harmful substance use in children of substance abusing parents: A longitudinal register-based study on a complete birth cohort born in 1991. | JÀÀskelΓ€inen M et al. | β | 2016 | β |
| Personality and Defense Styles: Clinical Specificities and Predictive Factors of Alcohol Use Disorder in Women. | Ribadier A et al. | β | 2016 | β |
| Association of substance dependence phenotypes in the COGA sample. | Wetherill L et al. | β | 2015 | β |
| Basal anxiety negatively correlates with vulnerability to ethanol-induced behavioral sensitization in DBA/2J mice: modulation by diazepam. | Botia B et al. | β | 2015 | β |
| Impact of Exposure to Childhood Maltreatment on Transitions to Alcohol Dependence in Women and Men. | Oberleitner LM et al. | β | 2015 | β |
| Interpretation of group-level factors from a large population dataset in the determination of ethyl glucuronide in hair. | Salomone A et al. | β | 2015 | β |
| Substance use in women: Current status and future directions. | Lal R et al. | β | 2015 | β |
| The National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) Waves 1 and 2: review and summary of findings. | Hasin DS et al. | β | 2015 | β |
| A randomized clinical trial of behavioral couples therapy versus individually based treatment for women with alcohol dependence. | Schumm JA et al. | β | 2014 | β |
| A research agenda for gender and substance use disorders in the emergency department. | Choo EK et al. | β | 2014 | β |
| Epidemiology of substance use in reproductive-age women. | McHugh RK et al. | β | 2014 | β |
| Prevalence and correlates of alcohol and cannabis use disorders in the United States: results from the national longitudinal study of adolescent health. | Haberstick BC et al. | β | 2014 | β |
| Public spending for illegal drug and alcohol treatment in hospitals: an EU cross-country comparison. | Lievens D et al. | β | 2014 | β |
| The association between inherited thrombophilia and recurrent pregnancy loss in Turkish women. | Isaoglu U et al. | β | 2014 | β |
| The neuroeconomics of alcohol demand: an initial investigation of the neural correlates of alcohol cost-benefit decision making in heavy drinking men. | MacKillop J et al. | β | 2014 | β |