= 554, ~21% exposed to sexual abuse and ~47% exposed to physical abuse, ~25% with AUD or CUD), the null association observed among AAs may relate to a lack of statistical power. Alternatively, distinct etiologic models of SUDs could be implicated, wherein rates of exposure to childhood trauma, substance use, and the role of other important risk factors (e.g. depression, parental SUD) in the relation of childhood trauma and SUD may differ by race/ethnicity. Further, the samples consisted of all-female populations residing in Missouri, limiting generalization of these findings to males, non-twins, and individuals in the US general population.