We examined association of rs12954372 with developmental trajectories of low theta EEG coherence in a longitudinal subsample of the discovery sample, including 2,316 adolescent/young adult offspring from COGA families. Significant effects of rs12954372 were driven by associations among females after age 18 (Supplemental Figure 2); the most significant p-value was observed for the association of rs12954372 and low theta P3-O1—P4-O2 coherence among females between ages 25-30 (2x10−9). Results from the sensitivity analysis, in which we controlled for the participant’s maximum number of drinks consumed in a typical week over the last 12 months, remained largely unchanged.
