dependence in GWAS (Uhl et al. 2008a). Gene is also found in GWAS in schizophrenia with P values of 10−4 (Sullivan et al. 2008) and shows CNVs potentially related to autism (Christian et al. 2008)Gene also shows association with adult ADHD in the GWAS by Neale et al. (2008a) and Lesch et al. (2008) rs1018040 Additive4.64E-061216772437IntergenicRegion lies close to linkage interval for anorexia nervosa (Devlin et al. 2002) rs1018040 Dominant2.97E-061216772437rs930421Recessive5.64E-06242834743Exon of MTA3Encodes metastasis associated 1 family, member 3, a component of the nucleosome-remodeling and histone- deacetylase multiprotein complex (NuRD). MTA3 plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and the regulation of E-cadherin levels. Expressed in multiple tissues, including brain, especially cerebellumClose to rs6719977 associated with FBAT-PC hyperactive–impulsive symptoms and rs10865184 showing association with ADHD symptom count in interaction with maternal criticismrs7577925Dominant2.55E-062133756989Intron of NAP5 (FLJ34870)Encodes Nck-associated protein 5, a peripheral clock protein 2. Expressed in brain (especially cerebellum) and other tissues. Function unknown. Within schizophrenia linkage region observed in meta-analysis (Lewis et al. 2003)rs1350666Additive8.30E-06475443454Within 15 kb upstream of EREGEncodes epiregulin, a member of the epidermal growth factor family, which can bind to the EGF receptor and may
