Our results underscore previous findings showing the high predictive value of neurophysiological brain function to predict/classify neurological disorder8. The EEG-FC discriminative features highlight the difference in the neural connectivity underlying resting state spontaneous processes (mind wandering, self-reference, and other introspective processes) between those with continued AUD vs remitted AUD. The continued AUD group showed a lower level of DMN connectivity confirming previous findings of aberrant DMN function in AUD and across psychiatric conditions such as depression, schizophrenia, and autism44,45. DMN activity during resting state is implicated in memory consolidation because of the commonality of neural systems to both processes, and, therefore, may be related to aberrant related mental processes such as working memory deficit46, inferior cognitive performance, inferior memory formation, and poor learning of cognitive skills47 in alcoholics. Indeed the continued AUD EA female group showed lower connectivity of parahippocampal with the anterior and posterior areas of the brain, previously implicated in memory48 and cognitive49 functions, and the AA males group showed lower connectivity in the precuneus/posterior cingulate, two of the main DMN hubs, which are suggested to play a
