With a prevalence of roughly 16%, study results revealed relatively high rates of current CUDs in hospitalized patients with BDI, surpassing the 9.4% rate reported in community samples of individuals with BD [6,7], but well within the range reported in other clinical samples of patients with BD [8,17,22]. Moreover, there was evidence for high clinical burden associated with CUDs in this otherwise acute sample of patients with BDI. Indeed, those with a comorbid CUD were significantly more likely to present with psychotic features, manic/mixed episode polarity, and comorbid nicotine, alcohol and non-cannabis drug use disorders. These data are highly consistent with findings reported in the broader cannabis use literature within BD [6,8,11,17] and further underscore the importance of careful monitoring of patients with BD and CUD comorbidity across clinical settings.
