Chunk #13 — Results — Top Bipolar Disorder susceptibility SNPs from GWA studies are enriched for mQTLs

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Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants.

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We also tested for enrichment of trans mQTLs among the top associated SNPs. At this initial mQTL threshold, there was no evidence for any significant excess. In 1000 simulated sets, the expected count of trans mQTLs was found to be 201.8 (SD=12.4); the observed count, however, was 199.