Chunk #42 — Results — RYR3: Regulation of initial sensitivity to ethanol in C. elegans, rapid tolerance to ethanol in Drosophila, and motivation to self administer alcohol in rats

Source

Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms.

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The mouse Ryr3 gene is localized to the support intervals for a complex group of ethanol behavioral QTL mapped to Chr 2 but Ryr3 basal whole brain expression (GN113; probeset 1427427_at) is not strongly correlated with ethanol-related phenotypes.