In conditional analyses, we identify 22 secondary SNVs (17 common, one rare, four low-frequency variants) that are conditionally independent of the BP associated SNVs at 16 previously reported loci at the time of analysis (Supplementary Table 8b; Supplementary Tables 11 and 12). One rare variant (rs138582164, MAF=0.1%) in the CDH17 locus anticipated to act as an exonic stop/gain mutation at the GEM gene is associated with a relatively large effect on PP (3.5 mm Hg per allele copy, Supplementary Table 8b). At three previously reported loci (EBF1, PDE3A, JAG1) we identify multiple independent secondary SNVs in addition to the previously reported SNVs (Supplementary Table 11).
