A PhenoScanner16 search showed that 27 of our 107 validated sentinel SNVs (or proxies; r2 ≥ 0.8) exhibit genome-wide significant associations with other traits (Supplementary Fig. 5), including coronary artery disease and myocardial infarction (where BP is likely on the causal pathway17), cardiovascular risk factors (e.g. lipids, height, body mass index) and non-cardiovascular traits (e.g. lung function, cancer, Alzheimer’s).
