Additionally, we evaluate our validated SNVs, where available, in cohorts of non-European ancestry9–11, while recognizing that these analyses are likely underpowered (Supplementary Table 10). We find concordance in direction of effect (P <0.05) for GWAS SNVs for all three BP traits among individuals of East Asian ancestry and for DBP for South Asian ancestry, also for exome SNVs among individuals of Hispanic ancestry, pointing to cosmopolitan effects for many of the BP associated variants.
