Mouse studies have carefully detailed the timing, subregional origin, and molecular events required for the production and survival of PVALB+ and SST+ expressing interneurons (Bandler et al., 2016). Multiple subtypes of SST+ interneurons exist in adult cortex, but it remains unknown whether specification is a result of intrinsic or extrinsic influences (Ma et al., 2006; Tasic et al., 2016; Zeisel et al., 2015).
