53.2 %, TC: 40.2 %, TT: 6.6 %) did not differ regarding alcohol intake or relationship with the parents (Table S4). No correlation was observed between AUDIT and parent-child relationship, except among TT carriers for whom problematic drinking was associated with poor parent-child relationship (r = 0.353; p < 0.008). The FKBP5 rs1360780 genotype modulated this association, with carriers homozygous for the T allele scoring the highest in AUDIT when experiencing a poor relationship with the parents (F (2, 832) = 3.6; p = 0.027) (Fig. 2).