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Chunk #7 — Introduction

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Disturbed resting state EEG synchronization in bipolar disorder: A graph-theoretic analysis.
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To our knowledge, no previous study has investigated the network topologies of resting-state EEG in BD. In this study, we investigated the differences in the organization of functional networks in BD by using a temporal synchronization measure to map the functional connectivity between brain regions and applying graph theoretical analysis to the resting-state SL data. We hypothesized that BD patients would show (1) decreased functional synchronization due to disrupted neural oscillations in the resting-state pathological network; (2) altered network efficiency resulting from the disruption of neuronal coordination; and (3) significant correlations between BD symptom measures and network characteristics.