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Chunk #13 — Methodology — Meta-analysis

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Genetic association study of childhood aggression across raters, instruments, and age.
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SNPs that had MAF < 0.01, Neff < 15 000, or were observed in less than two cohorts were removed from further analyses. SNP-heritabilities (\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$h_{SNP}^2$$\end{document}hSNP2) were estimated using LDSC [31]. rgs were calculated across stratified assessments of AGG using LDSC [29]. To ensure sufficient power for the genetic correlations, rg was calculated across stratified assessments of AGG if the Z-score of the \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$h_{SNP}^2$$\end{document}hSNP2 for the corresponding GWAMA was 4 or higher [29].