Chunk #11 — Materials and methods — Statistical power

Source

Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned.

Embedded

yes

Text

Detailed power calculations are provided in the Supplementary File 1. The MDD2000+ sample affords >90% power to detect an associated variant with MAF 0.36 and genotype relative risk (GRR) 1.33 (the median values across all published complex disease/trait GWAS, with P<5 × 10−8).28