We compared our results with those published for other GWAS of MDD. In particular, we conducted a formal genome-wide meta-analysis for autosomal SNPs from MDD2000+, GAIN–MDD12 and UK15 studies (that is, the three largest MDD GWAS). The GAIN–MDD sample, after removing individuals related to Dutch cases or controls of MDD2000+, comprised 1696 MDD cases and 1634 screened controls and the UK sample comprised 1636 MDD cases and 1594 screened controls. Meta-analysis29 on the logistic regression results from each study, restricting the imputed SNPs to those with INFO scores between 0.8 and 1.1.
