MVP links genomic laboratory testing, survey-based self-report data, and EHR data, with the goal of enhancing precision medicine initiatives23. Enrolled participants reflect the population that utilizes the VA, with over-representation of older and male individuals, as well as higher rates of multiple morbidities and chronic conditions related to externalizing compared to the general population24,25. Participants are active users of the VA healthcare system. Informed consent and authorization per the Health Insurance Portability and Accountability Act (HIPAA) were the only inclusion criteria. Once enrolled, participants’ EHR data are linked with their genetic data. The current analysis uses Release 4 of MVP data [February 2022] and was approved by the VA Central Institutional Review Board (IRB). All participants provided written informed consent.