While there was no difference across groups in the rate of subjects receiving medication during their most severe affective episode, subjects were prescribed antidepressants (35%), benzodiazepines (16%), neuroleptics (18%), lithium (9%), anticonvulsants (13%), or a combination of these medications (23%). At the follow-up interview, no differences were found across groups in type and rate of medication for the treatment of the most severe affective episode. Patients were prescribed antidepressants (31%), benzodiazepines (8%), neuroleptics (13%), lithium (35%), and anticonvulsants (22%). At follow-up, 35% of the bipolar subjects in all groups took a combination of these compounds.