In the follow-up study, 16 SNPs showed association with at least nominal significance (p<0.05, two-sided), 15 of which (9 intragenic, 6 intergenic) were associated with the same allele as in the GWA study. The number of significantly replicated SNPs is higher than expected by chance (p=2.45×10-6). Three of the intragenic SNPs are derived from the 22 SNPs selected on the basis of the animal model (Table 1). This number is also significantly higher than that expected by chance (p=1.69×10-2).
