been mixed. Differences are often contingent upon the experimental or measurement procedure used. For instance, the ability to detect intra-line-pair differences seen in general activity, and other parameters, differs across three test procedures (i.e., Multiple Concentric Square Field, Open Field and Elevated Plus Maze: Roman et al., 2012). For further discussion, see Section 6 which describes published findings on differences between high and low alcohol-consuming rats across four of these line-pairs.
