A total of 419 discovered SNPs from 337 genomic regions were found to be associated with disease, 320 of those SNPs being reported for the first time in Europeans, 97 in East Asians and 2 in Africans (Table S4). In total, we gathered 543 replication reports, dealing with 227 out of the 419 discovered SNPs (Table S5). Out of the 543 replication reports, 210, 260 and 73 corresponded, respectively, to attempts performed on Europeans, East Asians and on Africans. Since East Asian and African GWAS are more recent, most of the replication attempts (465 out of 536, 87%) reported the replication status of discovered SNPs that had been reported for the first time in Europeans. Therefore, we focused on the subset of 465 replication attempts gathered for 190 associated SNPs discovered in European GWAS. Out of these, a total of 181, 225 and 61 replication attempts had been reported for Europeans, East Asians and Africans, respectively.
