In 2005, the NCI launched Transdisciplinary Research on Energetics and Cancer I (TREC I), a five-year, $54 million initiative focused on addressing the growing epidemic of overweight and obesity in the U.S., and its relationship to cancer. The goal of TREC Iwas to foster the TD integration of social, behavioral, and biological sciences to address obesity and overweight, physical inactivity, and poor diet within a cancer prevention and control context. From 2005-2010, TREC I funded four research centers (located at Case Western Reserve University, Fred Hutchinson Cancer Research Center, University of Minnesota and University of Southern California) to conduct research on cellular mechanisms, genetics, physiology, behavior, and socio-environmental influences using diverse approaches including animal models, human subjects, population data, and environmental data. It also funded an independent coordination center, located at the Fred Hutchinson Cancer Research Center. In 2011, the TREC initiative was renewed for another five years as “TREC II”, with support for research centers at four different institutions, and continuing support for the original coordination center. The present study focuses on TREC I.
