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Chunk #2 — BACKGROUND

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Real-world observations on neuroinflammation-related drug responses in Alzheimer's disease.
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In this study, we compared drug responses in AD between individuals with and without neuroinflammation-related conditions (e.g., AUD, epilepsy, HS, and TBI) in a quasi-difference-in-difference setting. We used a large-scale US nationwide health insurance claim data and covariate-adjusted Cox model to investigate frequent drugs. We identified drugs that might have potentially differential effects in AD in patients with neuroinflammation-related conditions compared to without.