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Chunk #23 — RESULTS — Pathway Analysis

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Ethanol treatment of lymphoblastoid cell lines from alcoholics and non-alcoholics causes many subtle changes in gene expression.
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Protein ubiquitination pathway and hypoxia signaling in the cardiovascular system were the only two pathways in common for treatment and phenotype. The only affected gene common to these two pathways is UBE2Q, a ubiquitin-conjugating enzyme, which was decreased in alcoholics and as a result of treatment by ethanol.