We compared the effects for the 97 BMI index SNP across these related traits using a one-sided binomial test of the number of concordant effects versus a null expectation of P = 0.5. Concordant and nominally significant (P < 0.05) SNP effects were similarly tested using a one-sided binomial test with a null expectation of P = 0.05. We evaluated significance in either test with a Bonferroni-corrected threshold of P = 0.002 (0.05/23 traits tested).
