Chunk #153 — V. “Generalization” of selected genome wide association results between related disorders and phenotypes — B. Convergence between human genome wide association studies of dependence on addictive substances and success in smoking cessation (Samples 5 and 6 vs 12–14)
A number of the reproducibly-positive genes identified by studies of methamphetamine dependence are also identified by clustered- positive results studies of Samples 12, 13 and 14 of European-American smokers who are successful vs unsuccessful in abstaining from smoking during clinical trials for smoking cessation. p values were 0.002 [34] for convergence with sample 13 and < 0.00001 for convergence with samples 12–14 taken together [36, 37] (Figure 5).
