Genotype array data for 20,183 ADHD cases and 35,191 controls were collected from 12 cohorts (Supplementary Table 1). These samples included a population-based cohort of 14,584 cases and 22,492 controls from Denmark collected by the Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH; Supplementary Figure 1), and 11 European, North American and Chinese cohorts aggregated by the Psychiatric Genomics Consortium (PGC). ADHD cases in iPSYCH were identified from the national Psychiatric Central Research Register psychiatric and diagnosed by psychiatrists at a psychiatric hospital according to ICD10 (F90.0), and genotyped using Illumina PsychChip. Designs for the PGC cohorts have been described previously24,25,31,32,22 (see Supplementary Information for detailed cohort descriptions). All relevant ethical permissions and informed consent were obtained for the included cohorts (See Supplementary Information for dertails about approval authorities).