Recent efforts have also begun to incorporate genetic information into prevention/intervention studies to test whether the effectiveness of intervention varies as a function of genetic predisposition (Brody et al., 2013). It is well-known that not all children benefit equally from intervention, and a growing number of studies demonstrate that intervention effectiveness varies as a function of genotype (Albert et al., 2015, Bakermans-Kranenburg & Van Ijzendoorn, 2011, Brody et al., 2013). For example, one study found that children who were more biologically sensitive to stress (as indexed by carriers of one or two copies of A allele of a variant of NR3C1, a glucocorticoid receptor gene) had higher rates of externalizing behaviors in the control condition and lower rates of externalizing behaviors in the intervention condition in the Fast Track project (Albert et al., 2015). Many of these studies have focused on candidate genes (e.g., Bakermans-Kranenburg et al., 2008; Beach et al., 2010), and, thus are interesting more from a proof of principle standpoint at this time. However, as we have robust genome-wide polygenic scores and identified genes from large-scale gene
