We limit additional comment to genes of particular interest based upon existing data. In the gene-wide analysis of schizophrenia, as in the single SNP analysis of the same dataset20, we identified NOS1, RPGRIP1L, OPCML, TMEM108, and SIL1 as genes of potential interest. In bipolar disorder, we identified DPP10, RNPEPL1, CMTM8, DFNB31, LAMP3, TDRD9, PALB2, CDC25B, CAPN6 all of which had at least one polymorphism within the reference sequence that was associated at p<10−5 (3). Other than to note that the use of gene-wide tests flagged up many of the putative hits in the original studies, we do not discuss those genes any further since they have been considered in the original manuscripts.
