RelCheck (version 0.67; Boehnke and Cox, 1997; Broman and Weber, 1998) and PREST (version 3.0; McPeek and Sun, 2000) were used to screen for Mendelian errors and familial misspecifications, such as cases of non-paternity, and genotypes producing Mendelian errors were deleted. In the Finnish sample, three markers and six individuals with success rates below 70% were excluded. Two nuclear families were excluded due to an excess of Mendelian errors. Two MZ pairs were detected and one individual from each pair deleted. Two sibpairs with too low IBS-sharing were excluded. In the Australian sample, one marker with an error rate of 38% was excluded. Four MZ pairs were detected and one individual from each pair deleted, and five sibpairs with too low IBS-sharing were excluded. Please see Saccone et al. (2007a) and Loukola et al. (2008) for additional details on genotyping procedures.
