Specific to alcohol genetics research, participants expressed serious misgivings about providing DNA samples, citing worries about the implications of disclosing such personal information for research purposes. For example, participants expressed concerns about the impact of the discovery of an illness on their health insurance, and what it would mean for them to know if they had a predisposition to an alcohol use disorder. Participants also made references to previous research misconduct (e.g., Henrietta Lacks, The Tuskegee Syphilis Study) as reasons to mistrust researchers collecting biological samples, conducting genetic studies, and studying racial/ethnic minorities. These concerns help explain why Latinos may be less willing to participate in alcohol studies collecting biological samples, and in alcohol genetics research in particular. It may improve recruitment among Latinos if alcohol genetics researchers address these concerns directly to reduce the reasonable reluctance to participate in alcohol genetics studies. Similarly, concerns voiced by our female participants regarding uncertainty of genetic information and over personal and/or familial safety, and by our male participants regarding informational and motivational interests, could also be addressed directly to improve participation. One